A Non-Invasive Method to Detect Alzheimer’s Disease

Research from our group has shown a link between MRI-based hippocampal volume estimates and biomarkers found in patients years before cognitive decline. Specifically, a recent paper from our group, Tardif et al. (2017) suggest that hippocampal subfield volume and extra-hippocampal white matter microstructure demonstrate a complex pattern where an initial volume increase is followed by decline among asymptomatic individuals who, in some instances, may be a decade or more away from onset of cognitive or functional impairment associated with Alzherimer’s disease.

To learn more about how to identify individuals at risk for Alzheimer’s Disease, check out the video below for Dr. Mallar Chakravarty’s interview with Mutsumi Takahashi on CTV Montreal News.

We are going to SfN's 2017 Conference!

The CoBrA Lab will be at the Society for Neuroscience’s annual meeting in Washington, DC from November 11-15. Two of our lab members, Sejal Patel and Stephanie Tullo, will be presenting posters during the afternoon poster sessions on November 14th and 15th respectively. Sejal will be presenting her project titled “Vertex-wise and region of interest heritability analysis of human brain cortical thickness and surface area using a twin and non-twin siblings design” and Stephanie will be presenting her project titled “MR-based age- and sex-related effects on the striatum, globus pallidus and thalamus in healthy individuals across the adult lifespan”. Check out the abstracts here. For more information about SfN and the meeting, check out their website.

Happy Halloween from the CoBrA Lab!


CoBrA Lab at the SToP-AD annual gala!


The CoBrA lab attended this year’s Centre for Studies on Prevention of Alzheimer’s Disease (StoP-AD Centre) annual gala. The StoP-AD Centre is a joint collaboration between McGill University and the Douglas Institute which is dedicated to the prevention of AD. Specifically, the PREVENT-Alzheimer program studies Alzheimer’s disease in its pre-symptomatic stages in the hopes of finding strategies that can slow or reverse brain changes that may occur in older people who do not suffer from dementia but have a parental history of Alzheimer’s disease.

As a collaborating investigator, Dr. Mallar Chakravarty attended the annual gala along with the CoBrA lab members working on the Alzheimer’s Disease Biomarker study. We were pleased to have been a part of the day’s events which thanked the participants for dedicating their time to help Alzheimer’s research.

For more information about the PREVENT-AD program or the SToP-AD centre, visit the centre’s website.

Congratulations to Colleen on winning a 2017 Brain@McGill Undergraduate Prize

The CoBrA lab would like to congratulate Colleen Rollins on being awarded the 2nd place Brain@McGill Prize for Neuroscience Undergraduate Research. The Brain@McGill has established this award to recognize the importance of the next generation of promising young neuroscientists in advancing our understanding of the brain. Colleen was awarded this prize for her research investigating the impact of midlife obesity on Alzheimer’s disease (AD) pathology in a mouse model of Alzheimer’s disease. For more information about Colleen’s project, click here.